HCID 58823012, compound → 3-(2-Chloro-4-hydroxy-phenyl)-2-methoxy-propionic acid ethyl ester

HRID 459211Notes

Reaction equation

HRID 459211 reaction equation
[CH2:1]([O:3][C:4](=[O:24])[CH:5]([O:22][CH3:23])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13]CC2C=CC=CC=2)=[CH:9][C:8]=1[Cl:21])[CH3:2]>C(OCC)(=O)C>[CH2:1]([O:3][C:4](=[O:24])[CH:5]([O:22][CH3:23])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][C:8]=1[Cl:21])[CH3:2]

Participants

3

Reactant 1

HCID 58823012HCID 58823012, compound

Product 1

HCID 588230243-(2-Chloro-4-hydroxy-phenyl)-2-methoxy-propionic acid ethyl ester

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

3-(4-Benzyloxy-2-chloro-phenyl)-2-methoxy-propionic acid ethyl ester in ethyl acetate was treated with Pd(C) and H2 under balloon pressure. Then filtered through celite and concentrated to give the title compound.

Workup

  1. filtrationThen filtered through celite and
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-89d9d909162840a184ccdf8522abc132
Source dataset
uspto-grants-2007_03
Patent number
US07192982B2

Reaction notes

Loading…