Lithium Hydroxide → (2S)-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-2-propoxy-propionic acid

HRID 459272Notes

Reaction equation

HRID 459272 reaction equation
C([O:3][C:4](=[O:35])[C@@H:5]([O:31][CH2:32][CH2:33][CH3:34])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][CH2:16][O:17][C:18]2[CH:23]=[CH:22][C:21]([O:24][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)=[CH:20][CH:19]=2)=[CH:9][CH:8]=1)C.[Li+].[OH-]>>[O:24]([C:21]1[CH:20]=[CH:19][C:18]([O:17][CH2:16][CH2:15][CH2:14][O:13][C:10]2[CH:9]=[CH:8][C:7]([CH2:6][C@H:5]([O:31][CH2:32][CH2:33][CH3:34])[C:4]([OH:35])=[O:3])=[CH:12][CH:11]=2)=[CH:23][CH:22]=1)[C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

Participants

3

Reactant 2

HCID 3939Lithium HydroxideHCID 58822857(S)-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-2-propoxy-propionic acid ethyl ester

Product 1

HCID 10225859(2S)-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-2-propoxy-propionic acid

Procedure

The title compound was prepared from (S)-3-{4-[3-(4-Phenoxy-phenoxy)-propoxy]-phenyl}-2-propoxy-propionic acid ethyl ester by the standard hydrolysis procedure C (LiOH). MS(ES) for C27H30O6 [M−H]−: 449.2

Sources & evidence

ORD record
ord-ce9428ba201c427e815ac56bff3815b9
Source dataset
uspto-grants-2007_03
Patent number
US07192982B2

Reaction notes

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