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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459287Generated: October 29, 2026

HCID 426846, compound → HCID 58822564, compound

https://huagongshe.com/reaction/459287

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 426846HCID 426846—
ReactantHCID 58822797HCID 58822797—
ProductHCID 58822564HCID 58822564—

Reaction Steps

The title compound was prepared from (2S)-3-{4-[3-(4-hydroxy-phenoxy)-propoxy]-phenyl}-2-methoxy-propionic acid ethyl ester (Example 263, Step B) and methanesulfonic acid 3-dimethylaminopropyl ester (Step A) following the procedure described for Example 264. 1H-NMR (CDCl3, 200.15 MHz): δ 7.14 (d, 2H, J=7.8), 6.83–6.77 (m, 6H), 4.10–4.04 (m, 5H), 3.95–3.89 (m, 4H), 3.37 (s, 3H), 3.16–3.13 (m, 2H), 3.06–2.99 (m, 2H), 2.77 (s, 6H), 2.21–2.15 (m, 4H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-163f285d6d7b4bc8b325dd35cb1a1233
Source noteuspto-grants-2007_03