Sodium Hydroxide → HCID 58822680, compound

Participants

Reaction Steps

The title compound was prepared from (2S)-3-{4-[3-(4′-cyano-biphenyl-4-yloxy)-propoxy]-phenyl}-2-methoxy-propionic acid ethyl ester (Step A) via the standard hydrolysis procedure C (NaOH). 1H-NMR (MeOD, 300.15 MHz): δ 7.77 (s, 4H), 7.64 (d, 2H, J=8.7), 7.18 (d, 2H, J=8.5), 7.07 (d, 2H, J=8.7), 6.86 (d, 2H, J=8.3), 4.24 (t, 2H, J=6.3), 4.17 (t, 2H, J=6.3), 3.84–3.74 (m, 1H), 3.03–2.81 (m, 2H), 2.26 (qn, 2H, J=6.0).

Provenance & Evidence