Sodium Hydroxide → HCID 178496732, compound

Participants

Reaction Steps

The title compound was prepared from (2S)-2-methoxy-3-(4-{3-[4′-(1H-tetrazol-5-yl)biphenyl-4-yloxy]-propoxy}-phenyl)-propionic acid ethyl ester (Step A) via the standard hydrolysis procedure C (NaOH). 1H-NMR (MeOD, 300.15 MHz): δ 8.09 (d, 2H, J=8.3), 7.70 (d, 2H, J=8.3), 7.62 (d, 2H, J=8.7), 7.18 (d, 2H, J=8.5), 7.05 (d, 2H, J=8.7), 6.86 (d, 2H, J=8.7), 4.23 (t, 2H, J=6.0), 4.17 (t, 2H, J=6.1), 3.83 (dd, 1H, J=8.3, 4.2), 3.36 (s, 3H), 2.99 (dd, 1H, J=14.1, 4.0), 2.84 (dd, 1H, J=13.9, 8.1), 2.26 (qn, 2H, J=6.3).

Provenance & Evidence