Sodium Hydroxide → HCID 10273308, compound

Participants

Reaction Steps

The title compound was prepared from (2S)-2-ethoxy-3-{4-[3-(4-morpholin-4-yl-phenoxy)-propoxy]-phenyl}-propionic acid ethyl ester (Step A) by standard hydrolysis procedure C (NaOH). 1H-NMR (CDCl3, 200.15 MHz): δ 9.90 (s, 1H), 7.30 (d, 2H, J=9.1), 7.10 (d, 2H, J=8.4), 6.91 (d, 2H, J=9.1), 6.75 (d, 2H, J=8.8), 4.18–3.90 (m, 9H), 3.43–3.33 (m, 7H), 3.02 (dd, 1H, J=14.3, 4.8), 2.90 (dd, 1H, J=14.3, 7.0), 2.18 (qn, 2H, J=5.9).

Provenance & Evidence