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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459458Generated: October 29, 2026

Water → HCID 23712812, compound

https://huagongshe.com/reaction/459458

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantLithium HydroxideHCID 3939—
ReactantHCID 17842376HCID 17842376—
SolventTetrahydrofuranHCID 8028—
ProductHCID 23712812HCID 23712812107.6%

Reaction Steps

Water (6.0 ml) and lithium hydroxide (99.7 mg) were added to a solution of 2-methoxycarbonyl-5-methyl-4,5,6,7-tetrahydrooxazolo[5,4-c]pyridine (800 mg) in tetrahydrofuran (24 ml) at room temperature, and the mixture was stirred for 10 minutes. The reaction mixture was concentrated under reduced pressure to obtain the title compound (825 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192968B2
Source datasetuspto-grants-2007_03
ORD IDord-2fb317a880104a709680ef255a5ac435
Source noteuspto-grants-2007_03