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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459577Generated: October 29, 2026

Hydrochloric Acid → HCID 58822199, compound

https://huagongshe.com/reaction/459577

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantLithium 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylateHCID 23704331—
ReactantHCID 58822150HCID 58822150—
SolventEthanolHCID 702—
ProductHCID 58822199HCID 58822199—

Reaction Steps

(1R*,2R*,4S*)-N2-tert-Butoxycarbonyl-N1-[(5-chloroindol-2-yl)carbonyl]-4-ethoxycarbonyl-1,2-cyclohexanediamine was treated with a saturated ethanol solution of hydrochloric acid and then condensed with lithium 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]-pyridine-2-carboxylate in a similar manner to Example 118 to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192968B2
Source datasetuspto-grants-2007_03
ORD IDord-2982c4ceb9954bf1a1d1a3bb9263e046
Source noteuspto-grants-2007_03