Potassium Hydroxide → HCID 86760461, compound

Participants

Reaction Steps

1 g of Ethyl [S]-2-methyl-3-oxo-heptanoate, 0.5 g of KOH and 15 MeOH were stirred at 50° C. for 4 hrs. Then MeOH was removed and the residue is mixed with water, neutralized with conc.HCl and extracted with methylene chloride. The combined organic phase was washed with water for 3–4 times and dried over MgSO4. After evaporation of solvent, 0.8 g of product was obtained (yield 95%).

Provenance & Evidence