HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459854Generated: November 1, 2026
Hydrochloric Acid → HCID 82243366, compound
https://huagongshe.com/reaction/459854
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methyl acetoacetate | HCID 7757 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 6-Chloro-1-oxo-1lambda~5~-quinoline | HCID 12378925 | — |
| Product | HCID 82243366 | HCID 82243366 | — |
Reaction Steps
Methyl 3-oxobutyrate was added to an acetic anhydride solution of 6-chloroquinoline 1-oxide, followed by 30 minutes of stirring at an oil bath temperature of 40° C. Thus obtained compound was added to 10% hydrochloric acid and the mixture was reacted at room temperature to obtain methyl (6-chloroquinolin-2-yl)acetate. The compound was further treated in a similar manner to Reference Example 11, Example 22 and Example 4, successively, to obtain an objective compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07196080B2 |
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| Source dataset | uspto-grants-2007_03 |
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| ORD ID | ord-88f34cd4bdf5492599dd48c5a97e0a6b |
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| Source note | uspto-grants-2007_03 |
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