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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 45993Generated: October 28, 2026

Trifluoroacetic acid → HCID 57989597, compound

https://huagongshe.com/reaction/45993

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 57989587HCID 57989587—
SolventDichloromethaneHCID 6344—
ProductHCID 57989597HCID 57989597—

Reaction Steps

To a cold (0° C.) solution of (S)-tert-butyl 2-((1-(4-methoxy-2,6-dimethyl-phenylsulfonyl)indolin-2-yl)methoxy)acetate (0.5 mmol) in dichloromethane (6 ml) was added TFA (1.5 ml) and the reaction mixture was stirred at room temperature for 2 h. The solvent was evaporated under reduced pressure and the crude product was used in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08541573B2
Source datasetuspto-grants-2013_09
ORD IDord-2632ec5561054550ad1e95e54da237c4
Source noteuspto-grants-2013_09