HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4,5-difluorobenzoyl Isocyanate → HCID 18445937, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4,5-difluorobenzoyl Isocyanate | HCID 11557583 | — |
| Reactant | HCID 18445938 | HCID 18445938 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 18445937 | HCID 18445937 | — |
Reaction Steps
1-[3-Amino-5-(piperidine-1-sulfonyl)thiophen-2-yl]piperidine-4-carboxylic acid (0.2 g of crude product) is dissolved in 2 ml of acetonitrile and admixed with the equimolar solution of 2-chloro-4,5-difluorobenzoyl isocyanate in acetonitrile, and the mixture is stirred at RT. After 3 hours, the solid is filtered off with suction and dried under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07196114B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-2dd4f6921ff047e79a97ee0d5f8291ef |
| Source note | uspto-grants-2007_03 |