反应详情

To a solution of N,N′-bis[5-(3,4,5-trimethoxyphenyl)-2-pyridyl]-N,N′-dimethylethylenediamine (40.0 mg, 0.070 mmol) in methanol (5.0 mL) was added a 1.0 M aqueous methanesulfonic acid (0.14 mL, 0.14 mmol), and the reaction mixture was concentrated under reduced pressure. Ethanol (5.0 mL) was added to the residue, and the mixture was concentrated under reduced pressure. The residue was recrystallized from methanol-diethyl ether to yield the title compound as a pale, yellow crystalline powder (melting point: 204.0–206.0° C.) (32.0 mg, yield: 60%).

1. concentrationthe reaction mixture was concentrated under reduced pressure
2. additionEthanol (5.0 mL) was added to the residue
3. concentrationthe mixture was concentrated under reduced pressure
4. customThe residue was recrystallized from methanol-diethyl ether