Dodecanoyl chloride → HCID 10161285, compound

Participants

Reaction Steps

The p-aminophenol-β-D-glucopyranoside (250 mg) thus obtained was dissolved in tetrahydrofuran (20 ml), and lauroyl chloride (300 mg) and triethylamine (1.0 g) were added. The reaction mixture was refluxed for 5 hours. The reaction solution was filtered to remove solids, and the filtrate was evaporated under vacuum to give a dry solid. The residue was purified by silica gel chromatography using a tetrahydrofuran/chloroform mixed solvent (1/1, volume ratio) as an eluant, and dodecanoylaminophenol-β-D-glucopyranoside was thus obtained.

Provenance & Evidence