反应详情

The p-aminophenol-β-D-glucopyranoside (250 mg) thus obtained was dissolved in tetrahydrofuran (20 ml), and lauroyl chloride (300 mg) and triethylamine (1.0 g) were added. The reaction mixture was refluxed for 5 hours. The reaction solution was filtered to remove solids, and the filtrate was evaporated under vacuum to give a dry solid. The residue was purified by silica gel chromatography using a tetrahydrofuran/chloroform mixed solvent (1/1, volume ratio) as an eluant, and dodecanoylaminophenol-β-D-glucopyranoside was thus obtained.

1. temperatureThe reaction mixture was refluxed for 5 hours
2. filtrationThe reaction solution was filtered
3. customto remove solids
4. customthe filtrate was evaporated under vacuum
5. customto give a dry solid
6. customThe residue was purified by silica gel chromatography