Lithium Hydroxide → 6-[(2-Benzylmercapto-1-phenyl-1H-benzimidazol-6-yl]oxy]Hexanoic Acid

HRID 460542Notes

Reaction equation

HRID 460542 reaction equation
C[O:2][C:3](=[O:33])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:11]=[CH:12][C:13]2[N:17]=[C:16]([S:18][CH2:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[N:15]([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[C:14]=2[CH:32]=1.[OH-].[Li+]>>[CH2:19]([S:18][C:16]1[N:15]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[C:14]2[CH:32]=[C:10]([O:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:33])=[O:2])[CH:11]=[CH:12][C:13]=2[N:17]=1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 3939Lithium HydroxideHCID 694316006-[(2-Benzylmercapto-1-phenyl-1H-benzimidazol-6-yl)oxy]Hexanoic Acid Methyl Ester

Product 1

HCID 102040236-[(2-Benzylmercapto-1-phenyl-1H-benzimidazol-6-yl]oxy]Hexanoic Acid

Procedure

235 mg of 6-[(2-benzylmercapto-1-phenyl-1H-benzimidazol-6-yl)oxy]hexanoic acid methyl ester was reacted with lithium hydroxide according to general operating instructions 3. 179 mg was obtained.

Workup

  1. custom179 mg was obtained

Sources & evidence

ORD record
ord-c3181276abf44cdcaa9504f9e4e45e28
Source dataset
uspto-grants-2007_03
Patent number
US07196202B2

Reaction notes

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