Potassium Carbonate → HCID 60078000, compound

HRID 460599Notes

Reaction equation

HRID 460599 reaction equation
[OH:1][C:2]1[C:10]2[CH:9]=[C:8]([C:11]3[O:12][C:13]([CH2:16][CH3:17])=[N:14][N:15]=3)[O:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.S(C1C=CC([N+]([O-])=O)=CC=1)(O[CH2:22][C@H:23]1[O:25][CH2:24]1)(=O)=O.C(=O)([O-])[O-].[K+].[K+]>>[CH2:22]([O:1][C:2]1[C:10]2[CH:9]=[C:8]([C:11]3[O:12][C:13]([CH2:16][CH3:17])=[N:14][N:15]=3)[O:7][C:6]=2[CH:5]=[CH:4][CH:3]=1)[C@H:23]1[O:25][CH2:24]1

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 10868995(S)-(+)-Glycidyl-4-nitrobenzoateHCID 135794318HCID 135794318, compound

Product 1

HCID 60078000HCID 60078000, compoundYield 98.6%

Procedure

By the reactions in the same manner as in Starting Material Synthesis Example 1 using 2-(4-hydroxybenzo(b)furan-2-yl)-5-ethyl-1,3,4-oxadiazole (3.1 g) obtained in Starting Material Synthesis Example 75, (S)-glycidyl nosylate (3.5 g) and potassium carbonate (5.6 g), the title compound (3.8 g) was obtained as pale-yellow crystals.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-54262a045df9403f98f73dd943751910
Source dataset
uspto-grants-2007_03
Patent number
US07196199B2

Reaction notes

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