Isopropyl iodide → HCID 22729172, compound

HRID 460630Notes

Reaction equation

HRID 460630 reaction equation
[H-].[Na+].[CH3:3][O:4][CH2:5][O:6][C:7]1[C:15]2[CH:14]=[C:13]([C:16]3[O:20][C:19](=[O:21])[NH:18][N:17]=3)[O:12][C:11]=2[CH:10]=[CH:9][CH:8]=1.I[CH:23]([CH3:25])[CH3:24]>>[CH3:24][CH:23]([O:21][C:19]1[O:20][C:16]([C:13]2[O:12][C:11]3[CH:10]=[CH:9][CH:8]=[C:7]([O:6][CH2:5][O:4][CH3:3])[C:15]=3[CH:14]=2)=[N:17][N:18]=1)[CH3:25]

Participants

4

Reactant 3

HCID 6362Isopropyl iodideHCID 24758Sodium hydrideHCID 22729062HCID 22729062, compound

Product 1

HCID 22729172HCID 22729172, compoundYield 86.2%

Procedure

By the reactions in the same manner as in Starting Material Synthesis Example 117 using sodium hydride (0.28 g), 5-(4-(methoxymethyloxy)benzo(b)furan-2-yl)-2,3-dihydro-1,3,4-oxadiazol-2-one (1.5 g) and 2-iodopropane (1.1 g), the title compound (1.5 g) was obtained as brown crystals.

Sources & evidence

ORD record
ord-f6d86d1b87d540dfb61f43b8c3a2c0b0
Source dataset
uspto-grants-2007_03
Patent number
US07196199B2

Reaction notes

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