Hydrazine → HCID 747844, compound

HRID 460763Notes

Reaction equation

HRID 460763 reaction equation
[NH2:1][NH2:2].[N:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][C:11]=2[S:13](Cl)(=[O:15])=[O:14])[CH:6]=[CH:5][CH:4]=1>CO>[N:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][C:11]=2[S:13]([NH:1][NH2:2])(=[O:15])=[O:14])[CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 292208-Quinolinesulfonyl chloride

Product 1

HCID 747844HCID 747844, compoundYield 71.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
5 °C

Procedure

A 500 ml Erlenmeyer flask equipped with a magnetic stirrer and a thermometer is charged with 200 ml of methanol and 3.40 g (0.10 mol) of 95% hydrazine. The solution is cooled to 5° C, and 11.38 g (0.05 mol) of 8-quinolinesulfonyl chloride is added in small portions at a rate such that the reaction temperature does not exceed 15° C. After the reaction is complete, the solution is allowed to warm slowly to room temperature. The precipitating solid is filtered off to give 8.00 g of 8-quinolinesulfonyl hydrazine (C9H9N3O2S), m.p. 135°-137° C.

Workup

  1. customA 500 ml Erlenmeyer flask equipped with a magnetic stirrer
  2. customdoes not exceed 15° C
  3. temperatureto warm slowly to room temperature
  4. filtrationThe precipitating solid is filtered off

Sources & evidence

ORD record
ord-73064a78213e4e018a439d753566ba47
Source dataset
uspto-grants-1977_12
Patent number
US04061639

Reaction notes

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