HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 4-(2,4-Dichloro-5-sulfamoylphenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-(2,4-Dichloro-5-sulfamoylphenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol-hydrobromide | HCID 21394768 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(2,4-Dichloro-5-sulfamoylphenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol | HCID 21394769 | — |
Reaction Steps
7.4 g of 4-(2,4-dichloro-5-sulfamoylphenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol-hydrobromide in 60 ml of methanol were combined with 4 ml of triethylamine, heated for 5 minutes to 50° C on the steam bath and precipitation was effected with 250 ml of water. M.p. 187°-190° C (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04061647 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-036c84906728406fba97afbd7312af42 |
| Source note | uspto-grants-1977_12 |