反应详情

By the procedure described in Example 25(A) only substituting for cis-2-phenylcyclopentylamine hydrochloride an appropriate amount of trans-2-phenylcyclopentylamine hydrochloride, M.P. 142°-143° C, the hydrochloride salt of trans-2-cyclohexylcyclopentylamine is obtained, M.P. 199°-200° C. Following the procedure of Example 23 only substituting for cis-2-phenylcyclopentylamine hydrochloride and appropriate amount of trans-2-cyclohexylcyclopentylamine hydrochloride and employing a reaction time of 38 days, the desired product is obtained, M.P. 208°-210° C.

1. customa reaction time of 38 days