Lactic Acid → HCID 86735245, compound

HRID 461107Notes

Reaction equation

HRID 461107 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([OH:16])[CH2:12][S:11][C:10](=[N:13][CH3:14])[N:9]2[CH3:15])=[CH:4][C:3]=1[S:17](=[O:20])(=[O:19])[NH2:18].[C:21]([OH:26])(=[O:25])[CH:22]([CH3:24])[OH:23]>C(O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([OH:16])[CH2:12][S:11][C:10](=[N:13][CH3:14])[N:9]2[CH3:15])=[CH:4][C:3]=1[S:17](=[O:19])(=[O:20])[NH2:18].[C:21]([O-:26])(=[O:25])[CH:22]([CH3:24])[OH:23]

Participants

4

Reactant 2

HCID 612Lactic AcidHCID 721562-Chloro-5-(4-hydroxy-3-methyl-2-(methylimino)-4-thiazolidinyl)benzenesulfonamide

Product 1

HCID 86735245HCID 86735245, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To 1.5 g of 4-(4-chloro-3-sulfamoylphenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol 0.7 g of lactic acid were added in 10 ml of ethanol, the mixture was stirred for 3 hours at room temperature and precipitated with diisopropyl ether. After decanting of the solvent the oil was dissolved in water and lyophilized. The result was a colorless, amorphous solid substance that was decomposed from 120° C onwards γC=N 1630 cm-1.

Workup

  1. customprecipitated with diisopropyl ether
  2. customAfter decanting of the solvent the oil
  3. dissolutionwas dissolved in water
  4. customwas decomposed from 120° C onwards γC=N 1630 cm-1

Sources & evidence

ORD record
ord-1439a57a158f4ae5b6defda473978260
Source dataset
uspto-grants-1977_12
Patent number
US04061761

Reaction notes

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