2-Chloro-5-(4-hydroxy-3-methyl-2-(methylimino)-4-thiazolidinyl)benzenesulfonamide → HCID 131710962, compound

HRID 461108Notes

Reaction equation

HRID 461108 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([OH:16])[CH2:12][S:11][C:10](=[N:13][CH3:14])[N:9]2[CH3:15])=[CH:4][C:3]=1[S:17](=[O:20])(=[O:19])[NH2:18].[C:21]([OH:28])(=[O:27])/[CH:22]=[CH:23]\[C:24]([OH:26])=[O:25]>C(O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([OH:16])[CH2:12][S:11][C:10](=[N:13][CH3:14])[N:9]2[CH3:15])=[CH:4][C:3]=1[S:17](=[O:19])(=[O:20])[NH2:18].[C:21]([O-:28])(=[O:27])/[CH:22]=[CH:23]\[C:24]([O-:26])=[O:25]

Participants

4

Reactant 2

HCID 721562-Chloro-5-(4-hydroxy-3-methyl-2-(methylimino)-4-thiazolidinyl)benzenesulfonamideHCID 444266Maleic Acid

Product 1

HCID 131710962HCID 131710962, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1.5 g of 4-(4-chloro-3-sulfamoylphenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol were stirred in 10 ml of ethanol with 0.7 of maleic acid for 1 hour at room temperature, the salt desired was precipitated with 50 ml of diisopropyl ether and crystallized under fresh diisopropyl ether/ethyl acetate to yield colorless crystals which melted at 167° C (decomposition).

Workup

  1. customthe salt desired was precipitated with 50 ml of diisopropyl ether
  2. customcrystallized under fresh diisopropyl ether/ethyl acetate
  3. customto yield colorless crystals which melted at 167° C (decomposition)

Sources & evidence

ORD record
ord-1f80ee468f3b4e2a8610138d681372c7
Source dataset
uspto-grants-1977_12
Patent number
US04061761

Reaction notes

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