HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromo-4'-chloro-3'-sulfamoylacetophenone → 3-Ethyl-4-(4-chloro-3-sulfamoylphenyl)-2-isopropylimino-1,3-thiazolidine-4-ol-hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromo-4'-chloro-3'-sulfamoylacetophenone | HCID 12952390 | — |
| Reactant | 1-Ethyl-3-isopropylthiourea | HCID 19650595 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 3-Ethyl-4-(4-chloro-3-sulfamoylphenyl)-2-isopropylimino-1,3-thiazolidine-4-ol-hydrochloride | HCID 22760539 | — |
Reaction Steps
6.2 g of 2-bromo-4'-chloro-3'-sulfamoylacetophenone and 2.92 g of 1-ethyl-3-isopropylthiourea were heated in 40 ml of acetone for 15 minutes to 40° C, the mixture was stirred for another 30 minutes at room temperature and the crystals were filtered.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04061761 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-a86e179a5d4c4cf3b5479c5b39579ddc |
| Source note | uspto-grants-1977_12 |