Bromine → 2-Bromo-4'-chloro-3'-dimethylsulfamoylacetophenone

HRID 461192Notes

Reaction equation

HRID 461192 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[CH:4][C:3]=1[S:11](=[O:16])(=[O:15])[N:12]([CH3:14])[CH3:13].[Br:17]Br>C(O)(C)C>[Br:17][CH2:9][C:8]([C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[C:3]([S:11](=[O:16])(=[O:15])[N:12]([CH3:13])[CH3:14])[CH:4]=1)=[O:10]

Participants

4

Reactant 2

HCID 24408BromineHCID 22760438HCID 22760438, compound

Product 1

HCID 204768462-Bromo-4'-chloro-3'-dimethylsulfamoylacetophenone

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

7.9 g of 4'-chloro-3'-dimethylsulfamoylacetophenone were reacted according to Example 1a) with 4.8 g of bromine and worked up. Colorless crystals from isopropanol, melting point: 98° C.

Sources & evidence

ORD record
ord-9a90a5cfe7f046b1a6cae1ff99ddcfa6
Source dataset
uspto-grants-1977_12
Patent number
US04061761

Reaction notes

Loading…