HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Fluoro-3'-nitroacetophenone → 3'-Amino-4'-fluoroacetophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Fluoro-3'-nitroacetophenone | HCID 2734612 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3'-Amino-4'-fluoroacetophenone | HCID 10606953 | — |
Reaction Steps
39 g of 4'-fluoro-3'-nitroacetophenone, melting point: 44° C, were hydrogenated in 390 ml of methanol at 20 atm. and 40° C in the presence of Raney-Nickel to give the 3'-amino-4'-fluoro-acetophenone, melting point: 70° C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04061761 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-f99e5ea552214f1dbffc37f86dab6365 |
| Source note | uspto-grants-1977_12 |