Dimethylamine → HCID 22757747, compound

HRID 461372Notes

Reaction equation

HRID 461372 reaction equation
[CH2:1]([N:8]1[C:16]2[N:15]=[C:14]3[C:17](=[O:26])[C:18]4[CH:25]=[CH:24][CH:23]=[CH:22][C:19]=4[CH2:20][CH2:21][C:13]3=[C:12](Br)[C:11]=2[CH:10]=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:28][NH:29][CH3:30].CN>>[CH2:1]([N:8]1[C:16]2[N:15]=[C:14]3[C:17](=[O:26])[C:18]4[CH:25]=[CH:24][CH:23]=[CH:22][C:19]=4[CH2:20][CH2:21][C:13]3=[C:12]([N:29]([CH3:30])[CH3:28])[C:11]=2[CH:10]=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 674DimethylamineHCID 6329MethylamineHCID 227577601-benzyl-4-bromo-5,6-dihydrobenzo[5,6]cyclohepta[1,2-b]pyrazolo[4,3-e]-pyridin-11(1H)one

Product 1

HCID 22757747HCID 22757747, compound

Procedure

By substituting the product of Example 11 in the procedure of Example 5 and substituting dimethylamine for the methylamine, 1-benzyl-4-(dimethylamino)-5,6-dihydrobenzo[5,6]cyclohepta[1,2-b]pyrazolo[4,3-e]pyridin-11(1H)-one is obtained.

Sources & evidence

ORD record
ord-ecce790481ae49a5ba0db6e9686321ee
Source dataset
uspto-grants-1977_12
Patent number
US04062858

Reaction notes

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