Hydrochloric Acid → HCID 21393862, compound

HRID 461485Notes

Reaction equation

[Cl:1][C:2]1[C:11]([C:12]([F:15])([F:14])[F:13])=[C:10]2[C:5]([CH:6]=[CH:7][N:8]=[CH:9]2)=[CH:4][CH:3]=1.Cl>>[ClH:1].[Cl:1][C:2]1[C:11]([C:12]([F:15])([F:13])[F:14])=[C:10]2[C:5]([CH2:6][CH2:7][NH:8][CH2:9]2)=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 21393820HCID 21393820, compound

Product 1

HCID 21393862HCID 21393862, compound

Procedure

7-Chloro-8-trifluoromethylisoquinoline is converted to the hydrochloride and hydrogenated by the procedure of Example 9 to give 7-chloro-8-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride.

Sources & evidence

ORD record: ord-8850cca2f60443159f102b4f56e64af5
Source dataset: uspto-grants-1977_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04062961

Reaction notes

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