Methanol → HCID 88815335, compound

Participants

Reaction Steps

L-lysine monofluorophosphate was prepared by combining 29.2 grams of free-base lysine with 20 gm. (grams) of monofluorophosphoric acid in about 75 ml. of water. The resulting clear syrupy solution was poured into 750 ml. of a 50:50 mixture of methanol and ethanol (absolute) to precipitate the solid salt. The cake was collected after filtration and rinsed with methanol. The product (L-lysine monofluorophosphate) was then air dried. The L-lysine monofluorophosphate was tested in rat diets as described in Example I but at a level of 6.8 ppm fluoride. Caries reduction was 36%.

Provenance & Evidence