Water → HCID 178511811, compound

HRID 461679Notes

Reaction equation

HRID 461679 reaction equation
[NH2:1][C@H:2]([C:9]([OH:11])=[O:10])[CH2:3][C:4]1[N:8]=[CH:7][NH:6][CH:5]=1.[OH:12][P:13]([F:16])([OH:15])=[O:14].O>CO.C(O)C>[P:13]([F:16])([OH:15])([OH:14])=[O:12].[NH2:1][C@H:2]([C:9]([OH:11])=[O:10])[CH2:3][C:4]1[N:8]=[CH:7][NH:6][CH:5]=1

Participants

5

Reactant 3

HCID 962WaterHCID 24267Phosphorofluoridic acidHCID 178419078HCID 178419078, compound

Product 1

HCID 178511811HCID 178511811, compound

Reagents, catalysts & solvents 1

HCID 18681192Ethanol, mixt. with methanolSolvent

Procedure

L-histidine monofluorophosphate was prepared by combining 31 gm. of free-base L-histidine with 20 gm. of monofluorophosphoric acid in about 75 ml. of water. A clear syrup resulted. The syrup was poured into 750 ml. of a methanol-ethanol mixture. The precipitate (L-histidine monofluorophosphate) was collected and vacuum dried in a desiccator.

Workup

  1. customA clear syrup resulted
  2. additionThe syrup was poured into 750 ml
  3. customThe precipitate (L-histidine monofluorophosphate) was collected
  4. customvacuum dried in a desiccator

Sources & evidence

ORD record
ord-17e90312b2714341854be25add764976
Source dataset
uspto-grants-1977_12
Patent number
US04064138

Reaction notes

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