Piperidine → HCID 515311, compound

HRID 461958Notes

Reaction equation

HRID 461958 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][C:6]([C:8]1[CH:20]=[CH:19][C:18]2[C:17]3[C:12](=[CH:13][C:14]([C:21](=[O:27])[CH2:22][CH2:23][CH2:24][CH2:25]Cl)=[CH:15][CH:16]=3)[CH2:11][C:10]=2[CH:9]=1)=[O:7].[NH:28]1[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1>>[N:28]1([CH2:2][CH2:3][CH2:4][CH2:5][C:6]([C:8]2[CH:20]=[CH:19][C:18]3[C:17]4[C:12](=[CH:13][C:14]([C:21](=[O:27])[CH2:22][CH2:23][CH2:24][CH2:25][N:28]5[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]5)=[CH:15][CH:16]=4)[CH2:11][C:10]=3[CH:9]=2)=[O:7])[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 21392932HCID 21392932, compound

Product 1

HCID 515311HCID 515311, compound

Procedure

By the procedure of Example 7, 20.2g (0.05 mole) of 2,7-bis(5-chlorovaleryl)fluorene, prepared in Example 2, and 34.0g (0.4mole) of piperidine were reacted. The solid precipitate was recrystallized twice from methanol and chromatographed on alumina. Evaporation of solvent from the fraction collected gave the desired product. M.P. 124°-127° C, λmaxCHCl3 328, Elcm1% 731.

Workup

  1. customwere reacted
  2. customThe solid precipitate was recrystallized twice from methanol
  3. customchromatographed on alumina
  4. customEvaporation of solvent from the fraction
  5. customcollected

Sources & evidence

ORD record
ord-cb5a9c43631a4a4e954c5a1eff4e9f8e
Source dataset
uspto-grants-1977_12
Patent number
US04064347

Reaction notes

Loading…