HRID461965

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

结构：O=C(CCCN1CCCCC1)c1ccc2c(c1)C(=O)c1cc(C(=O)CCCN3CCCCC3)ccc1-2

HCID147584

2,7-Bis(1-oxo-4-(1-piperidyl)butyl)-9H-fluoren-9-one

C31H38N2O3

PRODUCTS

生成物

结构：Cl.Cl.O=C(CCCN1CCCCC1)c1ccc2c(c1)C(=O)c1cc(C(=O)CCCN3CCCCC3)ccc1-2

HCID147583

9H-Fluoren-9-one, 2,7-bis(1-oxo-4-(1-piperidinyl)butyl)-, dihydrochloride

C31H40Cl2N2O3

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

2,7-Bis(4-piperidinobutyryl)fluoren-9-one, prepared in Example 33, was dissolved in chloroform and the resulting solution acidified with ethereal HCl to give the desired product which was recrystallized once from water-isopropyl alcohol. M.P. 322°-323° C, λMaxH2O 284, E1cm1% 1,220.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-406852c9f0104ce28964ecd8b87b1353
来源数据集: uspto-grants-1977_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04064347
来源说明: uspto-grants-1977_12

反应 SMILES

[N:1]1([CH2:7][CH2:8][CH2:9][C:10]([C:12]2[CH:24]=[CH:23][C:22]3[C:21]4[C:16](=[CH:17][C:18]([C:25](=[O:35])[CH2:26][CH2:27][CH2:28][N:29]5[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]5)=[CH:19][CH:20]=4)[C:15](=[O:36])[C:14]=3[CH:13]=2)=[O:11])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[ClH:37]>C(Cl)(Cl)Cl>[ClH:37].[ClH:37].[N:1]1([CH2:7][CH2:8][CH2:9][C:10]([C:12]2[CH:24]=[CH:23][C:22]3[C:21]4[C:16](=[CH:17][C:18]([C:25](=[O:35])[CH2:26][CH2:27][CH2:28][N:29]5[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]5)=[CH:19][CH:20]=4)[C:15](=[O:36])[C:14]=3[CH:13]=2)=[O:11])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1