HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzaldehyde → 4-(Benzo[d]oxazol-2-yl)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzaldehyde | HCID 126 | — |
| Reactant | 2-Aminophenol | HCID 5801 | — |
| Reactant | Nitrobenzene | HCID 7416 | — |
| Product | 4-(Benzo[d]oxazol-2-yl)phenol | HCID 2785587 | 73% |
Reaction Steps
A mixture containing 5.45 g. (0.05 mole) of o-aminophenol and 6.10 g. (0.05 mole) of p-hydroxybenzaldehyde in 75 ml. of nitrobenzene was heated to reflux for 5 hr. On cooling to 30° a dark solid appears which was filtered, washed with hot toluene, and air-dried. Recrystallization from ethanol gave a 73% yield of 4-(2-benzoxazolyl)phenol (mp 255°-258°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04065427 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-3527316307514d1eb4762853e64f0e7f |
| Source note | uspto-grants-1977_12 |