反应详情

A mixture containing 5.45 g. (0.05 mole) of o-aminophenol and 6.10 g. (0.05 mole) of p-hydroxybenzaldehyde in 75 ml. of nitrobenzene was heated to reflux for 5 hr. On cooling to 30° a dark solid appears which was filtered, washed with hot toluene, and air-dried. Recrystallization from ethanol gave a 73% yield of 4-(2-benzoxazolyl)phenol (mp 255°-258°).

1. additionA mixture containing 5.45 g
2. temperatureto reflux for 5 hr
3. temperatureOn cooling to 30° a dark solid appears which
4. filtrationwas filtered
5. washwashed with hot toluene
6. customair-dried
7. customRecrystallization from ethanol