Hydrochloric Acid → HCID 291123, compound

HRID 462188Notes

Reaction equation

HRID 462188 reaction equation
O=[CH:2][C:3]1[CH:11]=[CH:10][C:8]([OH:9])=[C:5]([O:6][CH3:7])[CH:4]=1.[NH:12]1[CH2:18][C:16](=[O:17])[NH:15][C:13]1=[O:14].C(CN)O.Cl>O>[CH3:7][O:6][C:5]1[CH:4]=[C:3]([CH:11]=[CH:10][C:8]=1[OH:9])[CH:2]=[C:18]1[NH:12][C:13](=[O:14])[NH:15][C:16]1=[O:17]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 700EthanolamineHCID 1183VanillinHCID 10006Hydantoin

Product 1

HCID 291123HCID 291123, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Vanillin (3.04 g.) and hydantoin (2.0 g.) in water (20 ml) were heated on the steam-bath for a few minutes until dissolution occurred. Ethanolamine (0174 g.) was then added and the solution heated at 85°-90° (bath temperature) for 4.5 hours. The solution deposited crystals and solidified within 0.5 hours. Concentrated HCl (5 ml) was added, the mixture was refrigerated overnight (18 hours), filtered, water washed and dried. The title compound was obtained as a yellow solid (4.18 g; 93%), m.p. 266°-271° decomp.

Workup

  1. temperaturethe solution heated at 85°-90° (bath temperature) for 4.5 hours
  2. waitthe mixture was refrigerated overnight
  3. filtration(18 hours), filtered
  4. washwater washed
  5. customdried

Sources & evidence

ORD record
ord-0bf033c6646e4585962f719b2b38f4d7
Source dataset
uspto-grants-1977_12
Patent number
US04065570

Reaction notes

Loading…