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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 462413Generated: October 29, 2026

p-Toluenesulfonic acid → HCID 11543601, compound

https://huagongshe.com/reaction/462413

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Toluenesulfonic acidHCID 6101—
ReactantMorpholineHCID 8083—
ReactantSodium CyanideHCID 8929—
Reactant3,4-DichlorobenzaldehydeHCID 22710—
SolventTetrahydrofuranHCID 8028—
ProductHCID 11543601HCID 11543601—

Reaction Steps

A mixture of 3,4-dichlorobenzaldehyde, p-toluenesulfonic acid, morpholine and sodium cyanide in tetrahydrofuran is reacted to give α-(3,4-dichlorophenyl)-4-morpholineacetonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04515791
Source datasetuspto-grants-1985_05
ORD IDord-454a84003c004613ab976c3b985b0f1b
Source noteuspto-grants-1985_05