Ammonia → HCID 13365242, compound

Participants

Reaction Steps

Ethyl 4-formyl-2,6-dimethyl-3-benzoylaminobenzoate was used instead of the compound of formula (II) used in Example 1 and reacted with ammonia in the same way as in Example 1. The reaction product was chromatographed on a silica gel column in the same way as in Example 1. The solvent was evaporated, and the residue was recrystallized from diethyl ether/n-hexane to give 2-phenyl-7-ethoxycarbonyl-6,8-dimethylquinazoline having a melting point of 85° to 86° C. in a yield of 35% by weight.

Provenance & Evidence