Ammonia → HCID 13365246, compound

Participants

Reaction Steps

Instead of the compound of formula (II) used in Example 1, ethyl 4-formyl-2,6-dimethyl-3-acetylaminobenzoate was used and reacted with ammonia in the same way as in Example 1. The reaction product was chromatographed on a silica gel column in the same way as in Example 1. The solvent was evaporated, and the residue was recrystallized from ethanol/water to give 2-methyl-7-ethoxycarbonyl-6,8-dimethylquinazoline having a melting point of 84° to 86° C. in a yield of 40%.

Provenance & Evidence