Acetic Anhydride → HCID 13531510, compound

Participants

Reaction Steps

The product of Example 9 above, 2-amino-5-chloro-3-cyano-6-[(2-aminoethyl)thio]pyrazine (50 mg), was suspended in pyridine (0.5 ml), to which acetic anhydride (0.5 ml) was then added. The reaction mixture was stirred at room temperature overnight (18 hours), after which ice was added. The product precipitated, was filtered, and washed with water (10 mg).

Provenance & Evidence