Piperazine → HCID 20150188, compound

HRID 462956Notes

Reaction equation

HRID 462956 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:22]2[CH2:27][CH2:26][O:25][CH2:24][CH2:23]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][CH2:14][CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[C:6]=2[N:7]=1.[NH:28]1[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]1>>[O:25]1[CH2:26][CH2:27][N:22]([C:4]2[C:5]3[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][CH2:14][CH2:15][C:16]4[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=4)[C:6]=3[N:7]=[C:2]([N:28]3[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]3)[N:3]=2)[CH2:23][CH2:24]1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 20150153HCID 20150153, compound

Product 1

HCID 20150188HCID 20150188, compound

Procedure

This compound was prepared analogous to Example 1 from 2-chloro-4-morpholino-8-(3-phenylpropyl-thio)-pyrimido-[5,4-d]-pyrimidine (m.p.: 127°-129° C.) and piperazine.

Sources & evidence

ORD record
ord-d9d83ecc16894e7fb44c0056228896ce
Source dataset
uspto-grants-1985_05
Patent number
US04518596

Reaction notes

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