Piperazine → HCID 20187360, compound

HRID 462960Notes

Reaction equation

HRID 462960 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:21]2[CH2:26][CH2:25][O:24][CH2:23][CH2:22]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][C:14]3[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=3)[C:6]=2[N:7]=1.[NH:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[CH3:20][C:17]1[CH:18]=[CH:19][C:14]([CH2:13][S:12][C:8]2[C:6]3[N:7]=[C:2]([N:27]4[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]4)[N:3]=[C:4]([N:21]4[CH2:26][CH2:25][O:24][CH2:23][CH2:22]4)[C:5]=3[N:11]=[CH:10][N:9]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 20150124HCID 20150124, compound

Product 1

HCID 20187360HCID 20187360, compound

Procedure

This compound was prepared analogous to Example 1 from 2-chloro-8-(4-methylbenzyl-thio)-4-morpholino-pyrimido-[5,4-d]-pyrimidine (m.p.: 177°-179° C.) and piperazine.

Sources & evidence

ORD record
ord-e32e894949b04fab9e74e5c7b4a2d00e
Source dataset
uspto-grants-1985_05
Patent number
US04518596

Reaction notes

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