Piperazine → HCID 12817052, compound
Reaction equation
[NH2:1][C:2]1[C:7]2[N:8]=[C:9](Cl)[N:10]=[C:11]([N:12]3[CH2:17][CH2:16][O:15][CH2:14][CH2:13]3)[C:6]=2[N:5]=[CH:4][N:3]=1.[NH:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[NH2:1][C:2]1[C:7]2[N:8]=[C:9]([N:19]3[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]3)[N:10]=[C:11]([N:12]3[CH2:17][CH2:16][O:15][CH2:14][CH2:13]3)[C:6]=2[N:5]=[CH:4][N:3]=1Participants
3
Procedure
This compound was prepared analogous to Example 118 from 8-amino-2-chloro-4-morpholino-pyrimido-[5,4-d]-pyrimidine (m.p.: 206°-208° C.) and piperazine.
Sources & evidence
- ORD record
- ord-b8fabcfa8bd947809b60a866f2ec19c0
- Source dataset
- uspto-grants-1985_05
- Patent number
- US04518596
Reaction notes
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