HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-3-Bromopropylphthalimide → {2-[(3-Aminopropyl)(3-nitropyridin-2-yl)amino]phenyl}(phenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-3-Bromopropylphthalimide | HCID 21611 | — |
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | {2-[(3-Nitropyridin-2-yl)amino]phenyl}(phenyl)methanone | HCID 13388384 | — |
| Product | {2-[(3-Aminopropyl)(3-nitropyridin-2-yl)amino]phenyl}(phenyl)methanone | HCID 53831951 | — |
Reaction Steps
[2-[(3-Nitro-2-pyridinyl)amino]phenyl]phenylmethanone is reacted with (a) sodium hydride in solvent followed by N-(3-bromopropyl)phthalimide. The product of (a) is reacted with alcholic hydrazine hydrate and acid to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04518603 |
| Source dataset | uspto-grants-1985_05 |
| ORD ID | ord-1fa9efa2ba1443e7aa7a724d0e8fb6a6 |
| Source note | uspto-grants-1985_05 |