Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | trans-Crotonyl chloride | HCID 643131 | — |
| Reactant | 3-Hydroxy-4-(trimethylammonio)butanoate hydrochloride | HCID 9794197 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 129843952 | HCID 129843952 | — |
Reaction Steps
8 cc (0.08 moles) of crotonyl chloride were added to a solution of carnitine hydrochloride (8 grams; 0.04 moles) in trifluoroacetic acid. The reaction mixture was kept under stirring at 50° C. overnight. Subsequently, ethyl ether was added to the mixture and a precipitate formed. The precipitate was filtered off and used as such in the subsequent reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04518613 |
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| Source dataset | uspto-grants-1985_05 |
|---|
| ORD ID | ord-3087bf949a194fdb9c900eb94a64657a |
|---|
| Source note | uspto-grants-1985_05 |
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