Diethyl Ether → HCID 129843952, compound

HRID 463041Notes

Reaction equation

HRID 463041 reaction equation
[C:1](Cl)(=[O:5])/[CH:2]=[CH:3]/[CH3:4].Cl.[OH:8][CH:9]([CH2:15][C:16](=[O:18])[O-:17])[CH2:10][N+:11]([CH3:14])([CH3:13])[CH3:12].C(OCC)C>FC(F)(F)C(O)=O>[C:1]([C:9]([CH2:15][C:16](=[O:17])[O-:18])([CH2:10][N+:11]([CH3:12])([CH3:13])[CH3:14])[OH:8])(=[O:5])/[CH:2]=[CH:3]/[CH3:4]

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 643131trans-Crotonyl chlorideHCID 97941973-Hydroxy-4-(trimethylammonio)butanoate hydrochloride

Product 1

HCID 129843952HCID 129843952, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Conditions

Temperature
50 °C

Procedure

8 cc (0.08 moles) of crotonyl chloride were added to a solution of carnitine hydrochloride (8 grams; 0.04 moles) in trifluoroacetic acid. The reaction mixture was kept under stirring at 50° C. overnight. Subsequently, ethyl ether was added to the mixture and a precipitate formed. The precipitate was filtered off and used as such in the subsequent reaction.

Workup

  1. customa precipitate formed
  2. filtrationThe precipitate was filtered off
  3. customsuch in the subsequent reaction

Sources & evidence

ORD record
ord-3087bf949a194fdb9c900eb94a64657a
Source dataset
uspto-grants-1985_05
Patent number
US04518613

Reaction notes

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