Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 4631Generated: October 28, 2026

Phosphorus oxychloride → N-Cyclohexyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]1,3,4-thiadiazole-2,5-diamine

https://huagongshe.com/reaction/4631

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantN-cyclohexyl-2-[[3-[3-(1-piperidinylmethyl)phenoxy]propyl]aminothioxomethyl]-hydrazine carboxamideHCID 13657340—
ProductN-Cyclohexyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]1,3,4-thiadiazole-2,5-diamineHCID 13657368—

Reaction Steps

The compound is prepared by a method analogous to that of Example 40 from N-cyclohexyl-2-[[3-[3-(1-piperidinylmethyl)phenoxy]propyl]aminothioxomethyl]-hydrazine carboxamide and phosphorus oxychloride. The analytical values are summarized in Table III.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04727081
Source datasetuspto-grants-1988_02
ORD IDord-e67f7b9458324899aa2bf340325e6943
Source noteuspto-grants-1988_02