Triethyl phosphite → HCID 20264366, compound

HRID 463609Notes

Reaction equation

HRID 463609 reaction equation
[F:1][C:2]([F:21])([F:20])[C:3]1[CH:19]=[CH:18][C:6]([O:7][C:8]2[CH:17]=[CH:16][C:11]3=[N+:12]([O-])[O:13][N:14]=[C:10]3[CH:9]=2)=[CH:5][CH:4]=1.P(OCC)(OCC)OCC>C(O)C>[F:21][C:2]([F:1])([F:20])[C:3]1[CH:4]=[CH:5][C:6]([O:7][C:8]2[CH:17]=[CH:16][C:11]3=[N:12][O:13][N:14]=[C:10]3[CH:9]=2)=[CH:18][CH:19]=1

Participants

4

Reactant 2

HCID 31215Triethyl phosphiteHCID 53773122HCID 53773122, compound

Product 1

HCID 20264366HCID 20264366, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following the procedure of Example 2, 5-(4-trifluoromethylphenoxy)benzo-2,1,3-oxadiazole N-oxide (0.7 g) and triethyl phosphite (5 ml) in 75 ml of ethanol are heated under reflux for 2 hours. The reaction is cooled and stripped, and the residue is purified to give 5-(4-trifluoromethylphenoxy)benzo-2,1,3-oxadiazole, m.p. 77°-78°.

Workup

  1. temperatureare heated
  2. temperatureunder reflux for 2 hours
  3. temperatureThe reaction is cooled
  4. customthe residue is purified

Sources & evidence

ORD record
ord-c9d8dfa175514b8899f081c2b402b831
Source dataset
uspto-grants-1985_10
Patent number
US04544400

Reaction notes

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