9-Methoxyacridine → HCID 178419977, compound

Participants

Reaction Steps

2.09 g of 9-methoxyacridine are dissolved in 50 ml of dry ethanol, treated with a solution of 1.98 g of 2-hydrazino-2-thiazoline hydrobromide in 50 ml of dry ethanol, heated to boiling under reflux for 1 hour and the solvent is removed in vacuo. The residue is treated with aqueous ammonia (1:5) and extracted with ethyl acetate. After drying the extract over sodium sulfate and evaporation, the material obtained is crystallized by the addition of pentane. There is obtained 9-acridanone (2-thiazolidinylidene)hydrazone of melting point 214°-215° (decomposition).

Provenance & Evidence