Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 463758Generated: October 29, 2026

Methyl iodide → 5-Methoxymethylbenzo[b]furan

https://huagongshe.com/reaction/463758

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantPotassium HydroxideHCID 14797—
Reactant1-Benzofuran-5-ylmethanolHCID 2795179—
SolventDimethyl SulfoxideHCID 679—
Product5-Methoxymethylbenzo[b]furanHCID 20265053—

Reaction Steps

To a stirred mixture of powdered KOH in dimethylsulfoxide is added 5-hydroxymethylbenzo[b]furan in dimethylsulfoxide. Then methyl iodide is added dropwise at ambient temperature over several minutes to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04544667
Source datasetuspto-grants-1985_10
ORD IDord-e005b215c04741cdbcd123a081bde0c3
Source noteuspto-grants-1985_10