HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Methoxyphenyl)acetic acid → 3-Methoxyphenylacetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Methoxyphenyl)acetic acid | HCID 15719 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Methoxyphenylacetyl chloride | HCID 2733246 | — |
Reaction Steps
Oxalyl chloride (57.1 g) is added to a stirred solution of 3-methoxyphenylacetic acid (49.85 g) in 300 ml of methylene chloride. The reaction mixture is stirred for 11/2 hr at RT, refluxed overnight, and then evaporated in vacuo. The residual product is used in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04544670 |
| Source dataset | uspto-grants-1985_10 |
| ORD ID | ord-eea52394c43a4fe0b98dbc4262e3de7a |
| Source note | uspto-grants-1985_10 |